What is significant etiological moment of the Hirschsprung disease:
A. Muscular layer hypertrophy of the large bowel
B. Deficiancy of the Meisner's and Ouerbach's gangliones
C. Dilatation of the large bowel
D. Muscular hypotrophy of the large bowel
E. Disorders of blood supply in large bowel
Answer: B. Deficiancy of the Meisner's and Ouerbach's gangliones